Steroids and derivatives
Sigma Aldrich Fine Chemicals Biosciences Estradiol benzoate European Pharmacopoeia (EP) Reference Standard | 50-50-0 | MFCD00003692 |
Estradiol benzoate European Pharmacopoeia (EP) Reference Standard | Mol Wt: 376.49 | 50-50-0 | MFCD00003692 |
Sigma Aldrich Fine Chemicals Biosciences Estrone 3-methyl ether >=97% (HPLC) | 1624-62-0 | MFCD00046228 | 1G
Estrone 3-methyl ether >=97% (HPLC) | Purity: >=97% (HPLC) | Mol Wt: 284.39 | 1624-62-0 | MFCD00046228 | 1G
Sigma Aldrich Fine Chemicals Biosciences beta-Estradiol 3-benzoate >=97% | 50-50-0 | MFCD00003692 | 1G
beta-Estradiol 3-benzoate >=97% | Purity: >=97% | Mol Wt: 376.49 | 50-50-0 | MFCD00003692 | 1G
Enzo Life Sciences U-73343 (25 mg). CAS: 142878-12-4
Inactive analog of U-73122 (BML-ST391) which only slightly inhibits phospholipase C. May be used as a negative control. Alternative name: 1-[6-[[(17beta)-3-Methoxyestra-1,3,5(10)-trien-17-yl]amino]hexyl]-pyrrolidine-2,5-dione. Purity: ≥98% (HPLC). Solubility: Soluble in methylene chloride or chloroform; slightly soluble in DMSO (2mg/ml) or 100% ethanol (1mg/ml); sparingly soluble in aqueous solutions. Long Term Storage: Ambient.
Medchemexpress LLC U-73343 | 142878-12-4 | 99.43% | 466.66 | 50 MG
U-73343 is an inactive analog of U-73122 that functions as a protonophore and can be used as a negative control. It inhibits acid secretion in a dose-dependent manner, irrespective of the stimulant. U-73122 is known as a phospholipase C (PLC) and 5-LO (5-lipoxygenase) inhibitor.
- Potently inhibits acid secretion.
- Does not inhibit K+-pNPPase or H+,K+-ATPase activity.
- Inhibits histamine-, carbachol-, and dbcAMP-stimulated aminopyrine accumulation in gastric glands.
Cayman Chemical Estradiol Benzoate
An estradiol analog; often used in combination with a progestin to induce estrus in domestic livestock; binds to human, murine, and chicken ERα IC50s = 22-28 nM)
Sigma Aldrich Fine Chemicals Biosciences Estradiol benzoate for system suitability European Pharmacopoeia (EP) Reference Standard | 50-50-0 | MFCD00003692
Estradiol benzoate for system suitability European Pharmacopoeia (EP) Reference Standard | Mol Wt: 376.49 | 50-50-0 | MFCD00003692 |
Medchemexpress LLC Octaarginine acetate | 98.3% | 1267.50 | 100 MG
Octaarginine acetate | 98.3% | 1267.50 | 100 MG
Medchemexpress LLC Bazedoxifene (acetate) | 198481-33-3 | 99.9% | C32H38N2O5 | 100 MG
Bazedoxifene acetate (TSE-424 acetate) is an oral, nonsteroidal selective estrogen receptor modulator (SERM) that targets ERα (23 nM) and ERβ (99 nM). It is used for osteoporosis research and also acts as an inhibitor of IL-6/GP130 protein-protein interactions, making it suitable for pancreatic cancer research.
- Used in osteoporosis research
- Inhibits IL-6/GP130 protein-protein interactions
- Utilized for pancreatic cancer research
- Targets ERα and ERβ
- Inhibits STAT3 phosphorylation
- Induces apoptosis in human pancreatic cancer cells
- Blocks cell migration in pancreatic cancer cells
Medchemexpress LLC Br-PEG3-ethyl acetat 25mg
Br-PEG3-ethyl acetate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]
Medchemexpress LLC Bazedoxifene acetate | 198481-33-3 | 99.9% | 10 MG
Bazedoxifene acetate is an orally active, nonsteroidal selective estrogen receptor modulator (SERM) supplied as a solid research reagent for studies of estrogen receptor signaling, osteoporosis, and cancer. It shows activity against ERα and ERβ and is used in biochemical and cell-based assays.
Medchemexpress LLC Melatonin-d3 (N-Acetyl-5-methoxytryptamine-d3) | 90735-69-6 | 99.1% | C13H13D3N2O2 | 5 MG
Melatonin-d3 is the deuterium labeled version of Melatonin. Melatonin is a hormone that activates melatonin receptors, playing a role in sleep and possessing antioxidative and anti-inflammatory properties. It is also identified as a selective ATF-6 inhibitor, inducing apoptosis in human hepatoma cells by downregulating COX-2, and can reduce palmitic acid-induced apoptosis in mouse granulosa cells by alleviating endoplasmic reticulum stress.
- Used as a tracer
- Serves as an internal standard for quantitative analysis
- Stable heavy isotopes for drug development quantitation
- Deuteration can influence pharmacokinetic and metabolic profiles
- Powder storage: -20°C for 3 years, 4°C for 2 years
- Solvent storage: -80°C for 6 months, -20°C for 1 month
Medchemexpress LLC Ibuprofen-d3 (sodium) | 1219805-09-0 | 99.2% | C13H14D3NaO2 | 5 MG
Ibuprofen-d3 (sodium) is a deuterated form of ibuprofen, a non-steroidal anti-inflammatory drug (NSAID), provided as a sodium salt. This substance is intended for laboratory research and manufacture, and is not fully validated for medical applications. It is stable under recommended storage conditions.
- Solid appearance, white to off-white
- Purity (HPLC): 99.21%
- Isotopic enrichment: 99.9%
- Suitable for laboratory chemicals and substance manufacturing
- Stable under recommended storage conditions